No Pills. Next Level Absorption.
30+ Years of Superior Results
Engineered with Patented Ingredients

Transform Food into Energy

Ensure you are getting the most out of your food intake, by helping your body absorb critical healthy nutrients.

Feel Young and Stay Healthy

Powered by nature’s most powerful antioxidant, Pycnogenol®, combat the signs of aging with this bestseller of over 30 years.

Prime™ Joint Support Formula by Isotonix®

Prime™ Joint Support Formula by Isotonix®

  • Supports Staying Comfortable and Active 
  • Helps Maintain Strong, Healthy Cartilage 
  • Keeps Your Joints Feeling Young 
Isotonix® Digestive Enzyme with Probiotics

Isotonix® Digestive Enzyme with Probiotics

  • Ensure Absorption of Essentials
  • Eat Your Favorites - Still Feel Great!
  • Weeds and Feeds Your Gut
  • Get the Most Nutrients From Food
Isotonix® Bromelain Plus

Isotonix® Bromelain Plus

  • For Athletes and Active Lifestyles 
  • Vital Support for Tissue Recovery 
  • Promotes a Healthy Immune System 
  • Nutrients to Support Joint Function 
  • Supports the Body's Normal Healing Process
Isotonix® Multivitamin Without Iron

Isotonix® Multivitamin Without Iron

  • Your Foundation for Overall Health
  • Packed with 20+ Nutritional Essentials
  • Available With or Without Iron
  • Formulated for Advanced Delivery
Isotonix® Calcium Plus

Isotonix® Calcium Plus

  • Superb for Skeletal Support
  • Blend of Vitamins C, D and Magnesium
  • Supports Heart Rhythm
  • The Premium Calcium Your Body Needs
Isotonix® Resveratrol

Isotonix® Resveratrol

  • Promotes Cardiovascular Health
  • Captures the Antioxidant Power of Wine
  • Called the "Magic Bullet Against Aging"
  • Helps Support Healthy Cell Turnover

Isotonix vs. Standard Pill

Traditional pills lose vital nutrients during digestive breakdown. Our advanced isotonic blends bypass this, optimized for instant delivery into your system.

Isotonix
Isotonix
Standard Pill

Standard Pill

Free of binders, fillers, coatings

Formulated to survive digestion

Delivered in 5 minutes

95% intestinal nutrient delivery

The Super Antioxidant In OPC-3, Pycnogenol®


Isotonix OPC-3 contains the only isotonic form of Pycnogenol®,
a natural plant extract from the bark of the French maritime pine tree and the most clinically researched and powerful bioflavonoids in the world.

The Super Antioxidant In OPC-3, Pycnogenol® The Super Antioxidant In OPC-3, Pycnogenol®

95%

Nutrients are absorbed within minutes due to isotonic delivery system

20x

OPC antioxidants are up to 20x stronger than vitamin C

10%

Improved blood vessel function after high-fat meals when using OPC-3

50x

Neutralizes free radicals up to 50x more than vitamin E

Isotonix® Daily Essentials Packets

Power your day with 100% of the vital nutrients you need in one serving with Isotonix® Daily Essentials Packets! Packed with four powerhouse bestsellers, get the unmatched delivery and bioavailability of isotonic vitamins and minerals on the go.

A single Isotonix Daily Essentials multivitamin caplet packet centered on a white background, surrounded by four circular callouts showing other included or companion products: OPC-3, Isotonix Advanced B-Complex, Calcium Plus, and Multivitamin. A single Isotonix Daily Essentials multivitamin caplet packet centered on a white background, surrounded by four circular callouts showing other included or companion products: OPC-3, Isotonix Advanced B-Complex, Calcium Plus, and Multivitamin.

OPC-3® #1 Best-Seller

30+ Years. Unrivaled.
Uncompromising.

Good Manufacturing Processes
Isotonic Delivery
No GMO
Black stopwatch with a purple marker on a white background, indicating 5 minutes. Black stopwatch with a purple marker on a white background, indicating 5 minutes.

:05 minutes

Isotonix Liquid Vitamins

  • Formulated to survive digestion.
  • Delivers concentrated nutrients to the site of absorption.
  • Contains no fillers or binders.
  • No artificial colors or flavors. 

Black stopwatch with a purple face showing 40 minutes on a white background Black stopwatch with a purple face showing 40 minutes on a white background

:40 minutes

Standard Vitamin Tablet

  • Contains lab-created coatings and lubricants.
  • Often contains artifical colors, nutrients and flavors.
  • Limited absorption of nutrient utilization.

Benefits

Illustration of the human digestive system on a white background Illustration of the human digestive system on a white background

Isotonix solutions enter the digestive tract in a form that supplies nutrients at just the right rate, eliminating the need for further breakdown in the stomach with a 95% absorption rate.

Illustration of the human digestive system on a purple background Illustration of the human digestive system on a purple background

Tablets and capsules may remain in your digestive tract for hours, due to the need to break them down. Unlike other products, Isotonix solutions are in a form that allows for quick absorption.

Pink glitter spilling out of a white container with a purple circle on a white background Pink glitter spilling out of a white container with a purple circle on a white background

Isotonix products are powders, none of the fillers, binders and coatings that are common to tablet manufacturing. As a result, the amount of time and work necessary to absorb a supplement is greatly decreased.

Isotonix OPC-3® for Adults & Children Ages 4+

Isotonix OPC-3® for Adults & Children Ages 4+ (30 servings)

Product Option
Product Option:
Code  13007
+ $0.70 / 2.0% Cashback
Supplement container with blue label on a dark background with glowing elements A purple cylindrical bottle of OPC-3 Bury berry-flavored chewable antioxidants, surrounded by floating and splashing berries on a dark purple background.

OPC-3® Burst

Flavorful Wellness, Anywhere you go.

Our Customer Reviews

A minimalist white abstract background with soft wavy lines and a dotted texture. A minimalist white abstract background with soft wavy lines and a dotted texture.
Logo with a colorful circular color wheel and the letter 'ix' in the center. Logo with a colorful circular color wheel and the letter 'ix' in the center.

Build Your Own Isotonix® Custom Cocktail

One Perfect Scoop.
Customized by You.

A close-up of an open silver supplement jar labeled 'isotonix CUSTOM COCKTAIL' with colorful powder bursting from the top, and the lid resting beside it on a light gray background. A close-up of an open silver supplement jar labeled 'isotonix CUSTOM COCKTAIL' with colorful powder bursting from the top, and the lid resting beside it on a light gray background.

The Science of Isotonix

Everything you eat and drink, including nutritional supplements, must be made isotonic before passing into your small intestine where it can be absorbed.

“Isotonic” means having the same fluid pressure as your other bodily fluids like blood and tears. When you eat food, drink a beverage, or take a pill or capsule, your stomach must first secrete diluting juices, enzymes, hydrochloric acid, and at least one vitamin-binding protein to continue the process of digestion. Muscular contractions of your stomach then mix the contents until a reasonably uniform solution is achieved. This process can take anywhere from 40 minutes to four hours.

In the time that it takes for most pills and capsules to disintegrate, and their contents to dissolve and transform to the proper isotonic state, much of their activity is lost. During digestion, the important micronutrients in pills and capsules can get trapped by fats, fibers, and tannins or inactivated by the highly acidic pH level of your stomach.

Breakfast scene with pancakes, fruit, and Isotonix digestive enzymes packaging on a marble surface. An overhead styled breakfast scene on a white marble surface showing two plates of pancakes with fruit, blueberries, kiwi, and orange slices, along with a box and individual packets of Xtendi Digestive Enzymes with Probiotics.

Why is gastric emptying time
stressed when talking about Isotonix

Nutrients that are already isotonic do not need to be broken down into an isotonic state. Therefore, gastric emptying occurs more rapidly. Biological sensors in the gastrointestinal tract detect that the ingested solution is isotonic and at a correct pH. This causes the pyloric valve at the lower end of the stomach to remain open, allowing the concentrated solution to be squirted into the small intestine by stomach contractions. Absorption of the nutrients by the intestinal mucosa then starts to occur.


– Jim Wilmer, PhD

About the Featured Ingredients

Resveratrol

Resveratrol is an ingredient that can be naturally found in the skin of red grapes and has been studied for its potential cardiovascular and cellular benefits. Resveravine®, a concentrated extract containing resveratrol, helps ensure that the body receives all of the benefits of resveratrol.

Pycnogenol

Pycnogenol is a natural plant extract from the bark of the maritime pine tree, which grows exclusively along the coast of southwest France in Les Landes de Gascogne. The extract has three basic properties-it is a powerful antioxidant, selectively binds to collagen and elastin, and promotes the production of endothelial nitric oxide, which supports normal vasodilation of blood vessels. More than 200 scientific articles and clinical trials have confirmed Pycnogenol's safety, absence of toxicity and clinical efficacy over the past 35 years. Today, Pycnogenol is one of the most researched ingredients in the natural product marketplace.

Wellmune

Wellmune is a natural yeast beta glucan derived from a proprietary strain of yeast, Saccharomyces cerevisiae. Wellmune works to support immune cells, which are part of the body’s natural defenses. When Wellmune is ingested, immune cells in the gastrointestinal tract take it up and transport it to the immune organs throughout the body. While there, immune cells, called macrophages, digest the Wellmune into smaller fragments and slowly release them over a number of days. As they are released, the fragments bind to specific receptors (CR3) on neutrophils, which are the most abundant immune cells in the body. Wellmune supports the activity of the neutrophils and prime them for their normal activity in the body, including promoting immune health. It also supports the activity of phagocytic cells, which engulf and destroy foreign bodies, thus promoting immune health. Clinical studies have shown that Wellmune promotes a healthy immune system. The molecular structure of Wellmune WGP, with its beta 1,3/1,6 branch points, is responsible for its unique biological activity.

Açai

Isotonix Açai Advanced Energy is derived from the berries of the açai palm of the Amazon rainforest. Isotonix Açai combines vitamins, guarana and taurine with the antioxidant properties of green tea, açai berries, mangosteen and pomegranate.

Bcaas

Branched chain amino acids (BCAA) are considered essential, as they cannot be synthesized by the human body and, therefore, must be consumed through diet or supplementation. Unlike other amino acids, BCAA are used primarily by skeletal muscle, making up 30-35 percent of the muscle tissue itself. These amino acids promote healthy muscle growth and retention. As aging occurs, the body’s ability to build and retain muscle tissue or size is reduced, which can result in weakness and frailty. Research has shown that supplementation with BCAA promotes muscle retention in older adults. Additionally, it has been shown that supplementation of BCAA during exercise supports muscle protein synthesis and inhibits protein catabolism (breakdown) and muscle fatigue. By using instantized BCAAs within the isotonic system, there is a quicker dissolution and increased bioavailability.

CoQ10

Coenzyme Q10 is a water-insoluble, wax-like substance that is part of the respiratory chain. In our cells, it helps to generate energy from oxygen, in the form of ATP, for the body. CoQ10 also exhibits activity as a free radical scavenger and an antioxidant.

Bromelain

As a mixture of proteases, bromelain has been used by Europeans for many years for its support of normal inflammatory response. Its components work to help support the body’s normal inflammatory response and support the healing process. This is important for healthy joint function and adequate tissue repair, which supports the body’s normal recovery process. Because these proteases can interfere with parts of the inflammatory cascade, supplementation may help to promote normal recovery after intense exercise.
Bromelain has been extensively studied both in experimental models and clinical studies for its effects on the inflammatory response. Research also shows that bromelain may help support healthy blood viscosity and blood platelet aggregation, promoting healthy circulation. It also supports normal levels of fibrin in the blood, which promotes normal healing.

Glucosamine

Glucosamine is a molecule that is naturally synthesized in the body from glucose and the amino acid glutamine. Glucosamine is an important constituent of glycosaminoglycans in cartilage matrix and synovial fluid. As our bodies age, we are less able to produce glucosamine, resulting in cartilage that is less flexible and weak. Although the mechanism is currently unclear, studies have shown that glucosamine supplementation can support normal, healthy cartilage cell production to help maintain overall joint health.

Folate

Folic acid is mainly found in fruits and vegetables. Dark leafy greens, oranges, orange juice, beans and peas are the best sources as well as Brewer’s yeast, which supplies additional B-vitamins. Folic acid plays a key role by boosting the benefits of vitamin B12 supplementation. These two B-vitamins join forces and work together in maintaining normal red blood cells. Folic acid assists in the normal utilization of amino acids and proteins as well as promoting the normal construction of the material for DNA and RNA synthesis. Scientific studies have found that when working in tandem with folic acid, vitamin B12 is capable of promoting a healthy cardiovascular and nervous system. Quatrefolic is the glucosamine salt of (6S)-5-methyltetrahydrofolate, the most active form of folate, as it is structurally analogous to the reduced and active form of folic acid. Because this form is naturally present in the body, it is much more bioavailable for its biological action without having to be metabolized in the body. This patented ingredient also provides greater stability and higher water solubility, perfect for Isotonix.

Lutein

Lutein is an organic pigment found in a small area of the retina responsible for central vision. According to recent research, lutein helps protect from oxidative stress and the high-energy photons of blue light. Various research studies have shown that a direct relationship exists between lutein intake and pigmentation in the eye.

*The FDA only evaluates foods and drugs, not supplements like these products. These products are not intended to diagnose, prevent, treat, or cure any disease.