Primary Benefits of Isotonix® Vision Formula with Lutein*:

• Promotes healthy vision
• Helps support healthy eye tissue and circulation
• Supports night vision
• Promotes healthy macular density
• May help maintain eye health as you age
• May slow effects of the aging process on eye health

Key Ingredients Found in Isotonix® Vision Formula with Lutein:

Vitamin A 5,000 IU (Beta-Carotene/Vitamin A pre-cursor)

Vitamin A is a fat-soluble vitamin. Sources of vitamin A include organ meats (such as liver and kidney), egg yolks, butter, carrot juice, squash, sweet potatoes, spinach, peaches, fortified dairy products and cod liver oil. Vitamin A is also part of a family of compounds including retinol, retinal and beta-carotene. Beta-carotene, also known as pro-vitamin A, can be converted into vitamin A when additional levels are required. All the body’s tissues for general growth and repair need vitamin A. Vitamin A helps to promote healthy night vision, support normal bone growth, and support an antioxidant defense and a healthy immune system.*

Vitamin C 75 mg (Ascorbic Acid)

Vitamin C is found in peppers (sweet, green, red, hot red and green chili), citrus fruits, brussels sprouts, cauliflower, cabbage, kale, collards, mustard greens, broccoli, spinach, guava, kiwi fruit, currants and strawberries. Nuts and grains contain small amounts of vitamin C. It is important to note that cooking destroys vitamin C activity.*

Vitamin C is integral in supporting a healthy immune system, promoting cardiovascular health, maintaining healthy cholesterol levels and providing an antioxidant defense. The body does not manufacture vitamin C on its own, nor does it store it. Therefore, vitamin C must be acquired through diet and supplementation.*

Vitamin E 33 IU (DL-Alpha-Tocopheryl-Acetate)

The most valuable sources of dietary vitamin E include vegetable oils, margarine, nuts, seeds, avocados and wheat germ. Safflower oil contains large amounts of vitamin E (about two thirds of the RDA in ¼ cup), and there are trace amounts in corn oil and soybean oil. Vitamin E is actually a family of related compounds called tocopherols and tocotrienols. Vitamin E is available in a natural or synthetic form. In most cases, the natural and synthetic forms are identical, except the natural form of vitamin E is better absorbed and retained in the body. The natural form of alpha-tocopherol is known as "d-alpha tocopherol." (The natural form is found in Isotonix Multivitamin.) The synthetic "dl-" form is the most common form found in dietary supplements. For those individuals watching their dietary fat consumption, which is relatively common in the world of dieting, vitamin E intake is likely to be low, due to a reduced intake of foods with high fat content.*

The main health benefit of supplemental vitamin E comes from its immune-boosting antioxidant activity. It is also promotes normal healing of wounds and is known to provide protection for the cardiovascular system. Vitamin E is one of the most powerful fat-soluble antioxidants in the body. In turn, vitamin E protects cell membranes from free radical damage.*

Lutein (7mg) and Zeaxanthin (1.4mg)

Lutein and Zeaxanthin are carotenoids found together in many fresh fruits and vegetables. Within the eye, they are found as pigments in the macula and retina. Lutein and Zeaxanthin act as antioxidants to protect the eye from free radical damage. They promote pigment density, a critical factor in the health of the macula and retina in relation to the clarity of the lens. They also act as filters of blue-light to promote the health of the photoreceptor cells of the retina from light damage. Blue-light wave lengths can generate free radical damage.

Bilberry Extract (50 mg)

Bilberry extract is derived from the leaves and berry-like fruit of a common European shrub closely related to the blueberry. Extracts of the ripe berry are known to contain flavonoid pigments known as anthocyanins. They act as powerful antioxidants. Scientific studies confirm a positive effect on vision and vein issues. Bilberry supports night vision and eases eyestrain while nourishing eye tissue, and supporting healthy circulation in the eye. Many of the bioflavanoids in bilberry have antioxidant and anti-inflammatory effects, strengthening the structural integrity of blood vessels and promoting healthy circulation to small capillaries that deliver oxygen and nutrients to the eyes. Bilberry extract supports capillaries and helps reduce bruising while promoting normal healing of wounds.

Eyebright 10mg (Euphrasia officinalis)

Eyebright is an annual plant with deeply-cut leaves and small, white or purple flowers variegated with yellow, native to Great Britain. There are over 20 species of eyebright that extend over Europe, Northern and Western Asia, and North America. The health-promoting portion of eyebright comes from fluid extracted just above the root only when the plant is in bloom.

Eyebright has been used by herbalists since the 16th century for promoting eye health.

Chromium 100 mcg (Argininate/Histidinate)

Chromium is found naturally in some cereals, meats, poultry, brewer’s yeast, broccoli, prunes mushrooms, fish and beer. Chromium is an essential trace mineral that plays an important role in glucose metabolism, regulation of insulin levels, and the maintenance of healthy blood levels of cholesterol and other fats. Chromium combines to form something in the body called glucose tolerance factor, or GTF, which helps maintain normal blood sugar levels. It is claimed that chromium helps to lower blood sugar, cholesterol and triglycerides levels. Chromium has been shown to help reduce overall body fat, control hunger and suppress appetite. Many people in the weight loss industry view chromium as an integral mineral in weight maintenance. Chromium may also contribute to an increase in lean body and muscle mass.*

Copper 100 mcg (Gluconate)

The richest sources of dietary copper derive from organ meats, seafood, nuts, seeds, wheat bran cereal, whole grain products and cocoa products. Copper may have some antioxidant properties and acts as a component of enzymes in iron metabolism. It is an essential trace mineral. Copper is needed in normal infant development, iron transport, bone strength, cholesterol metabolism, myocardial contractility, glucose metabolism, brain development and immune function.*

Zinc 7 mg (Lactate)

Zinc is largely found in fortified cereals, red meats, eggs, poultry and certain seafood, including oysters. It is a component of multiple enzymes and proteins. It is also involved in the regulation of gene expression. Zinc is an essential trace mineral that has functions in approximately 300 different enzyme reactions. Thus, zinc plays a part in almost all biochemical pathways and physiological processes. More than 90 percent of the body’s zinc is stored in the bones and muscles, but zinc is also found in virtually all body tissues. It has been claimed that zinc plays a role in wound healing, immune system support, promoting a healthy prostate gland and supports healthy sperm quality. Because zinc is involved in such a great number of enzymatic processes, it has been found to positively affect a large range of functions, including digestion, energy production, growth, cellular repair, collagen synthesis, bone strength, cognitive function and carbohydrate metabolism.*

Quercetin (25 mg)

Quercetin is a bioflavonoid that is an excellent antioxidant working synergistically with vitamin C to strengthen the walls of the intricate blood vessels in the eye. It also helps to maintain lens transparency. Quercetin has been shown to inhibit the enzyme, aldose reductase. Aldose reductase has been known to contribute to poor eye health.

L-Taurine (42 mg)

L-Taurine is a building block for all the other amino acids. It aids in the transport of potassium, sodium, calcium and magnesium in and out of cells, thus supporting the normal generation of nerve impulses. It is a non-protein amino acid and is found in high amounts in the brain, retina, myocardium, skeletal and smooth muscle, platelets and neutrophils. It is plentiful in the fluids of muscle, lungs and nerve tissue. Dietary taurine mainly comes from animal food sources. Taurine is also present, in lower levels, in plant food sources like seaweed. It is classified as an essential amino acid and supports micelle formation and fat absorption. Further, it promotes alertness, mental energy and focus. Taurine also has antioxidant properties and supports stable membranes. It may also help maintain a healthy cardiovascular system while also delivering detoxifying activities. It helps protect the eyes from the harmful effects of UV light and promotes the health of the membranes in the cones cells of the eye. It also supports healthy cholesterol and blood pressure levels. It may also help maintain a healthy cardiovascular system while also delivering detoxifying activities.*

Lycopene (2 mg)

Fruits and vegetables, such as tomatoes, pink grapefruit and watermelon receive their red pigmentation from a carotene called Lycopene. Lycopene is one of the carotenes and a member of the carotenoid family. Lycopene offers a wide range of benefits in helping maintain healthy cardiovascular health, prostate health and powerful antioxidant. More recent research suggests that lycopene, like beta-carotene, may play an important role in keeping vision healthy by preventing cataracts and Age-Related Macular Degeneration (AMD).

Scientific Support for Isotonix® Vision Formula with Lutein:

• Bahrami, H., et al. Lutein supplementation in retinitis pigmentosa: PC-based vision assessment in a randomized double-masked placebo-controlled clinical trial [NCT00029289]. BMC Ophthalmology. 6: 23, 2006.
• Bartlett, H. and Eperjesi, F. Age-related macular degeneration and nutritional supplementation: a review of randomized controlled trials. Ophthalmic & Physiological Optics. 23(5): 383-399, 2003.
• Bartlett, H. and Eperjesi, F. Age-related macular degeneration and nutritional supplementation: a review of randomized controlled trials. Ophthalmic & Physiological Optics. 23(5): 383-399, 2003.
• Berendschot, T., et al. Lens aging in relation to nutritional determinants and possible risk factors for age-related cataract. Archives of Ophthalmology. 120(12): 1732-1737, 2002.
• Berendschot, T., et al. Lens aging in relation to nutritional determinants and possible risk factors for age-related cataract. Archives of Ophthalmology. 120(12): 1732-1737, 2002.
• Bone, R, et al. Lutein and zeaxanthin dietary supplements raise macular pigment density and serum concentrations of these carotenoids in humans. Journal of Nutrition. 133(4): 992-998, 2003.
• Bone, R., et al. Lutein and zeaxanthin in the eyes, serum and diet of human subjects. Experimental Eye Research. 71(3): 239-245, 2000.
• Bone, R., et al. Macular pigment response to a supplement containing meso-zeaxanthin, lutein and zeaxanthin. Nutrition & Metabolism. 11: 4-12, 2007.
• Bone, R., et al. Macular pigment response to a supplement containing meso-zeaxanthin, lutein and zeaxanthin. Nutrition & Metabolism. 11: 4-12, 2007.
• Bressler, M., et al. Potential public health impact of Age-Related Eye Disease Study results: AREDS report no. 11. Archives of Ophthalmology. 121(11): 1621-1624, 2003.
• Cangemi, F. TOZAL Study: an open case control study of an oral antioxidant and omega-3 supplement for dry AMD. BMC Ophthalmology. 7: 3, 2007.
• Chasan-Taber, L., et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. The American Journal of Clinical Nutrition. 70(4): 509-516, 1999.
• Chitchumroonchokchai, C., et al. Xanthophylls and alpha-tocopherol decrease UVB-induced lipid peroxidation and stress signaling in human lens epithelial cells. Journal of Nutrition. 134(12): 3225-3232, 2004.
• Chitchumroonchokchai, C., et al. Xanthophylls and alpha-tocopherol decrease UVB-induced lipid peroxidation and stress signaling in human lens epithelial cells. Journal of Nutrition. 134(12): 3225-3232, 2004.
• Christian, P., et al. Zinc supplementation might potentiate the effect of vitamin A in restoring night vision in pregnant Nepalese women. The American Journal of Clinical Nutrition. 73(6): 1045-51, 2001.
• Congdon, N., et al. Responsiveness of dark-adaptation threshold to vitamin A and beta-carotene supplementation in pregnant and lactating women in Nepal. American Journal of Clinical Nutrition. 72(4): 1004-1009, 2000.
• Devamanoharan, P., et al. Prevention of lens protein glycation by taurine. Molecular and Cellular Biochemistry. 177(1-2): 245-250, 1997.
• Hammond Jr., B. and Johnson, M. The age-related eye disease study (AREDS). Nutrition Reviews. 60(9): 283-288, 2002.
• Hankinson, S., et al. Nutrient intake and cataract extraction in women: a prospective study. British Medical Journal. 305(6849): 335-339, 1992.
• Kassoff, A., et al. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Archives of Ophthalmology. 119(10): 1417-1436, 2001.
• Mares-Perlman, J., et al. Serum antioxidants and age-related macular degeneration in a population-based case-control study. Archives of Ophthalmology. 113(12): 1518-1523, 1995.
• Richer, S., et al. Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (Lutein Antioxidant Supplementation Trial). Optometry. 75(4): 216-230, 2004.
• Taren, D., et al. The night vision threshold test is a better predictor of low serum vitamin A concentration than self-reported night blindness in pregnant urban Nepalese women. Journal of Nutrition. 134(10): 2573-2578, 2004.
• Varma, S., et al. Diabetic cataracts and flavonoids. Science. 195(4274): 205-206, 1977.
• Wondmikun, Y. Dark adaptation pattern of pregnant women as an indicator of functional disturbance at acceptable serum vitamin A levels. European Journal of Clinical Nutrition. 56(5): 462-466, 2002.

What Makes Isotonix® Vision Formula with Lutein Unique?*

Maintaining vision health is vital, especially during the aging process. When light is reflected off an object, the light waves from the object enter the eye through the cornea, which is the transparent front part of the eye that covers the iris, pupil and anterior chamber. The light is then filtered through to the pupil, which is the black circular or slit shaped opening in the center of the iris that regulates the amount of light that enters the eye. The iris is the colored portion of the eye that controls the pupil. The light then continues through the lens, located behind the iris and pupil, and made up of transparent proteins called crystallins. The light waves are bent or converged by the lens and the cornea to just behind the surface of the lens where it is then reversed and inverted.

The light waves then pass through the vitreous humor, the clear gel between the lens and the retina, which is a thin layer of neural cells that lines the back of the eyeball. The macula is a small, yellowish spot located in the middle of the retina that is responsible for the detail of vision by providing visual sharpness and color perception. The retina consists of a large number of photoreceptor cells, which contain a particular protein molecule called an opsin. In humans, there are two types of opsins: rod opsins and cone opsins. Each opsin absorbs a photon (a particle of light) and transmits a signal to the cell through a signal transduction pathway, resulting in hyper-polarization of the photoreceptor. Within the retina, light waves are changed into electrical signals and then sent through the optic nerve, along the visual pathway, to the occipital cortex at the posterior or back of the brain. The brain is what actually reconstructs or interprets the electrical impulses into a picture.

The intricate process that contributes to visual degradation usually develops over a long time-period, making the need for a protective eye approach even more important. Free radical activity is a constant factor in the body’s metabolism. Waiting to begin an antioxidant defense against oxidative stress until the prime senior years may be too late. Promoting visual health is important and can be accomplished through a healthy diet, exercise and the right supplementation.

Isotonix Vision Formula with Lutein is an isotonic-capable dietary supplement, combining vitamins and minerals with lutein, quercetin, eyebright, zeaxanthin and bilberry, designed to promote healthy vision throughout the aging process. Isotonix Vision Formula helps maintain the structural integrity of blood vessels and capillaries, helps maintain the membranes of cone cells in the eyes, helps maintain lens transparency, helps strengthen the cells of the retina, and promotes healthy oxygen and nutrient flow to the eyes. The antioxidant properties of Isotonix Vision Formula help protect the eyes from oxidative stress. It promotes healthy macular density, promotes healthy vision and supports night vision.

Isotonic, which means “same pressure,” bears the same chemical resemblance of the body’s blood, plasma and tears. All fluids in the body have a certain concentration, referred to as osmotic pressure. The body’s common osmotic pressure, which is isotonic, allows a consistent maintenance of body tissues. In order for a substance to be absorbed and used in the body’s metabolism, it must be transported in an isotonic state.

Isotonix dietary supplements are delivered in an isotonic solution. This means that the body has less work to do in obtaining maximum absorption. The isotonic state of the suspension allows nutrients to pass directly into the small intestine and be rapidly absorbed into the bloodstream. With Isotonix products, little nutritive value is lost, making the absorption of nutrients highly efficient while delivering maximum results.

Related terms: Isotonix® Vision Formula with Lutein, vision formula, lutein, isotonix, isotonic, macular degeneration, eye health, vision health, vision, macula.

Frequently Asked Questions about Isotonix® Vision Formula with Lutein*:

How does the Isotonix Vision Formula with Lutein work?

In the Age-Related Eye Disease Study, sponsored by the National Institute of Health, ingredients like those in Isotonix Vision Formula with Lutein were found to support eye health. The antioxidants in Isotonix Vision Formula with Lutein promote a healthy eye by neutralizing free radicals.

How is the Isotonix Vision Formula with Lutein different from other vision formulas?

Isotonix Vision Formula with Lutein contains 14 of the known essential vitamins and minerals that contribute to overall vision health. Additionally, it is isotonic form, which contributes to maximum absorption by the body.

What if I am taking a prescription; is Isotonix Vision Formula with Lutein safe?

While all of the ingredients in Isotonix Vision Formula are found in nature and unlikely to interfere with any prescription, it would be wise to contact your physician before including this or any other dietary supplement in your nutritional regimen.

What studies have been done to show that the ingredients in Isotonix Vision Formula with Lutein are effective?

Studies show that the carotenoids: lutein, zeazanthin and B-C will help support eye health. According to the results of a government study led in part by researchers at Johns Hopkin’s Wilmer Eye Institute, if those who were at risk for vision degradation chose to use daily supplements of antioxidant vitamins and zinc, the risk of vision loss for more than 300,000 people could be avoided over the next five years.

In October 2001, the National Eye Institute published the results of a seven-year study called the Age-Related Eye Disease Study (AREDS). The study showed that a high dose combination of vitamin C, vitamin E, beta-carotene and zinc could significantly reduce the risk of certain factors leading to visual degradation by about 25 percent. A nutritional supplement featuring this unique combination could allow you to enjoy quality of eyesight into your golden years.

How many people are affected with vision loss?

It is estimated that 300,000 Americans are blind and nearly 13 million have partial vision loss due to poor eye health. Age-related macular degeneration is the leading cause of blindness in Americans ages 65 and older.

Is it ok for me to take additional vitamins?

Yes. Isotonix Vision Formula with Lutein pairs well with Isotonix® Multivitamin, Isotonix® Multi-Mineral and other great Market America vitamin and mineral products.

What is an antioxidant?

Antioxidants act as cell protectors by neutralizing free radicals. Free radicals are harmful byproducts that can cause cellular damage that can lead to serious health problems. Free radicals cause oxidative damage to the body, meaning premature aging, hardening of the arteries, stiffened joints and wrinkling of the skin. Air pollution, heavy exercise, stress and smoking can all contribute to creating harmful free radicals.

Primary Benefits of Isotonix® Vision Formula with Lutein*:

• Promotes healthy vision
• Helps support healthy eye tissue and circulation
• Supports night vision
• Promotes healthy macular density
• May help maintain eye health as you age
• May slow effects of the aging process on eye health

Key Ingredients Found in Isotonix® Vision Formula with Lutein:

Vitamin A 5,000 IU (Beta-Carotene/Vitamin A pre-cursor)

Vitamin A is a fat-soluble vitamin. Sources of vitamin A include organ meats (such as liver and kidney), egg yolks, butter, carrot juice, squash, sweet potatoes, spinach, peaches, fortified dairy products and cod liver oil. Vitamin A is also part of a family of compounds including retinol, retinal and beta-carotene. Beta-carotene, also known as pro-vitamin A, can be converted into vitamin A when additional levels are required. All the body’s tissues for general growth and repair need vitamin A. Vitamin A helps to promote healthy night vision, support normal bone growth, and support an antioxidant defense and a healthy immune system.*

Vitamin C 75 mg (Ascorbic Acid)

Vitamin C is found in peppers (sweet, green, red, hot red and green chili), citrus fruits, brussels sprouts, cauliflower, cabbage, kale, collards, mustard greens, broccoli, spinach, guava, kiwi fruit, currants and strawberries. Nuts and grains contain small amounts of vitamin C. It is important to note that cooking destroys vitamin C activity.*

Vitamin C is integral in supporting a healthy immune system, promoting cardiovascular health, maintaining healthy cholesterol levels and providing an antioxidant defense. The body does not manufacture vitamin C on its own, nor does it store it. Therefore, vitamin C must be acquired through diet and supplementation.*

Vitamin E 33 IU (DL-Alpha-Tocopheryl-Acetate)

The most valuable sources of dietary vitamin E include vegetable oils, margarine, nuts, seeds, avocados and wheat germ. Safflower oil contains large amounts of vitamin E (about two thirds of the RDA in ¼ cup), and there are trace amounts in corn oil and soybean oil. Vitamin E is actually a family of related compounds called tocopherols and tocotrienols. Vitamin E is available in a natural or synthetic form. In most cases, the natural and synthetic forms are identical, except the natural form of vitamin E is better absorbed and retained in the body. The natural form of alpha-tocopherol is known as "d-alpha tocopherol." (The natural form is found in Isotonix Multivitamin.) The synthetic "dl-" form is the most common form found in dietary supplements. For those individuals watching their dietary fat consumption, which is relatively common in the world of dieting, vitamin E intake is likely to be low, due to a reduced intake of foods with high fat content.*

The main health benefit of supplemental vitamin E comes from its immune-boosting antioxidant activity. It is also promotes normal healing of wounds and is known to provide protection for the cardiovascular system. Vitamin E is one of the most powerful fat-soluble antioxidants in the body. In turn, vitamin E protects cell membranes from free radical damage.*

Lutein (7mg) and Zeaxanthin (1.4mg)

Lutein and Zeaxanthin are carotenoids found together in many fresh fruits and vegetables. Within the eye, they are found as pigments in the macula and retina. Lutein and Zeaxanthin act as antioxidants to protect the eye from free radical damage. They promote pigment density, a critical factor in the health of the macula and retina in relation to the clarity of the lens. They also act as filters of blue-light to promote the health of the photoreceptor cells of the retina from light damage. Blue-light wave lengths can generate free radical damage.

Bilberry Extract (50 mg)

Bilberry extract is derived from the leaves and berry-like fruit of a common European shrub closely related to the blueberry. Extracts of the ripe berry are known to contain flavonoid pigments known as anthocyanins. They act as powerful antioxidants. Scientific studies confirm a positive effect on vision and vein issues. Bilberry supports night vision and eases eyestrain while nourishing eye tissue, and supporting healthy circulation in the eye. Many of the bioflavanoids in bilberry have antioxidant and anti-inflammatory effects, strengthening the structural integrity of blood vessels and promoting healthy circulation to small capillaries that deliver oxygen and nutrients to the eyes. Bilberry extract supports capillaries and helps reduce bruising while promoting normal healing of wounds.

Eyebright 10mg (Euphrasia officinalis)

Eyebright is an annual plant with deeply-cut leaves and small, white or purple flowers variegated with yellow, native to Great Britain. There are over 20 species of eyebright that extend over Europe, Northern and Western Asia, and North America. The health-promoting portion of eyebright comes from fluid extracted just above the root only when the plant is in bloom.

Eyebright has been used by herbalists since the 16th century for promoting eye health.

Chromium 100 mcg (Argininate/Histidinate)

Chromium is found naturally in some cereals, meats, poultry, brewer’s yeast, broccoli, prunes mushrooms, fish and beer. Chromium is an essential trace mineral that plays an important role in glucose metabolism, regulation of insulin levels, and the maintenance of healthy blood levels of cholesterol and other fats. Chromium combines to form something in the body called glucose tolerance factor, or GTF, which helps maintain normal blood sugar levels. It is claimed that chromium helps to lower blood sugar, cholesterol and triglycerides levels. Chromium has been shown to help reduce overall body fat, control hunger and suppress appetite. Many people in the weight loss industry view chromium as an integral mineral in weight maintenance. Chromium may also contribute to an increase in lean body and muscle mass.*

Copper 100 mcg (Gluconate)

The richest sources of dietary copper derive from organ meats, seafood, nuts, seeds, wheat bran cereal, whole grain products and cocoa products. Copper may have some antioxidant properties and acts as a component of enzymes in iron metabolism. It is an essential trace mineral. Copper is needed in normal infant development, iron transport, bone strength, cholesterol metabolism, myocardial contractility, glucose metabolism, brain development and immune function.*

Zinc 7 mg (Lactate)

Zinc is largely found in fortified cereals, red meats, eggs, poultry and certain seafood, including oysters. It is a component of multiple enzymes and proteins. It is also involved in the regulation of gene expression. Zinc is an essential trace mineral that has functions in approximately 300 different enzyme reactions. Thus, zinc plays a part in almost all biochemical pathways and physiological processes. More than 90 percent of the body’s zinc is stored in the bones and muscles, but zinc is also found in virtually all body tissues. It has been claimed that zinc plays a role in wound healing, immune system support, promoting a healthy prostate gland and supports healthy sperm quality. Because zinc is involved in such a great number of enzymatic processes, it has been found to positively affect a large range of functions, including digestion, energy production, growth, cellular repair, collagen synthesis, bone strength, cognitive function and carbohydrate metabolism.*

Quercetin (25 mg)

Quercetin is a bioflavonoid that is an excellent antioxidant working synergistically with vitamin C to strengthen the walls of the intricate blood vessels in the eye. It also helps to maintain lens transparency. Quercetin has been shown to inhibit the enzyme, aldose reductase. Aldose reductase has been known to contribute to poor eye health.

L-Taurine (42 mg)

L-Taurine is a building block for all the other amino acids. It aids in the transport of potassium, sodium, calcium and magnesium in and out of cells, thus supporting the normal generation of nerve impulses. It is a non-protein amino acid and is found in high amounts in the brain, retina, myocardium, skeletal and smooth muscle, platelets and neutrophils. It is plentiful in the fluids of muscle, lungs and nerve tissue. Dietary taurine mainly comes from animal food sources. Taurine is also present, in lower levels, in plant food sources like seaweed. It is classified as an essential amino acid and supports micelle formation and fat absorption. Further, it promotes alertness, mental energy and focus. Taurine also has antioxidant properties and supports stable membranes. It may also help maintain a healthy cardiovascular system while also delivering detoxifying activities. It helps protect the eyes from the harmful effects of UV light and promotes the health of the membranes in the cones cells of the eye. It also supports healthy cholesterol and blood pressure levels. It may also help maintain a healthy cardiovascular system while also delivering detoxifying activities.*

Lycopene (2 mg)

Fruits and vegetables, such as tomatoes, pink grapefruit and watermelon receive their red pigmentation from a carotene called Lycopene. Lycopene is one of the carotenes and a member of the carotenoid family. Lycopene offers a wide range of benefits in helping maintain healthy cardiovascular health, prostate health and powerful antioxidant. More recent research suggests that lycopene, like beta-carotene, may play an important role in keeping vision healthy by preventing cataracts and Age-Related Macular Degeneration (AMD).

Scientific Support for Isotonix® Vision Formula with Lutein:

• Bahrami, H., et al. Lutein supplementation in retinitis pigmentosa: PC-based vision assessment in a randomized double-masked placebo-controlled clinical trial [NCT00029289]. BMC Ophthalmology. 6: 23, 2006.
• Bartlett, H. and Eperjesi, F. Age-related macular degeneration and nutritional supplementation: a review of randomized controlled trials. Ophthalmic & Physiological Optics. 23(5): 383-399, 2003.
• Bartlett, H. and Eperjesi, F. Age-related macular degeneration and nutritional supplementation: a review of randomized controlled trials. Ophthalmic & Physiological Optics. 23(5): 383-399, 2003.
• Berendschot, T., et al. Lens aging in relation to nutritional determinants and possible risk factors for age-related cataract. Archives of Ophthalmology. 120(12): 1732-1737, 2002.
• Berendschot, T., et al. Lens aging in relation to nutritional determinants and possible risk factors for age-related cataract. Archives of Ophthalmology. 120(12): 1732-1737, 2002.
• Bone, R, et al. Lutein and zeaxanthin dietary supplements raise macular pigment density and serum concentrations of these carotenoids in humans. Journal of Nutrition. 133(4): 992-998, 2003.
• Bone, R., et al. Lutein and zeaxanthin in the eyes, serum and diet of human subjects. Experimental Eye Research. 71(3): 239-245, 2000.
• Bone, R., et al. Macular pigment response to a supplement containing meso-zeaxanthin, lutein and zeaxanthin. Nutrition & Metabolism. 11: 4-12, 2007.
• Bone, R., et al. Macular pigment response to a supplement containing meso-zeaxanthin, lutein and zeaxanthin. Nutrition & Metabolism. 11: 4-12, 2007.
• Bressler, M., et al. Potential public health impact of Age-Related Eye Disease Study results: AREDS report no. 11. Archives of Ophthalmology. 121(11): 1621-1624, 2003.
• Cangemi, F. TOZAL Study: an open case control study of an oral antioxidant and omega-3 supplement for dry AMD. BMC Ophthalmology. 7: 3, 2007.
• Chasan-Taber, L., et al. A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women. The American Journal of Clinical Nutrition. 70(4): 509-516, 1999.
• Chitchumroonchokchai, C., et al. Xanthophylls and alpha-tocopherol decrease UVB-induced lipid peroxidation and stress signaling in human lens epithelial cells. Journal of Nutrition. 134(12): 3225-3232, 2004.
• Chitchumroonchokchai, C., et al. Xanthophylls and alpha-tocopherol decrease UVB-induced lipid peroxidation and stress signaling in human lens epithelial cells. Journal of Nutrition. 134(12): 3225-3232, 2004.
• Christian, P., et al. Zinc supplementation might potentiate the effect of vitamin A in restoring night vision in pregnant Nepalese women. The American Journal of Clinical Nutrition. 73(6): 1045-51, 2001.
• Congdon, N., et al. Responsiveness of dark-adaptation threshold to vitamin A and beta-carotene supplementation in pregnant and lactating women in Nepal. American Journal of Clinical Nutrition. 72(4): 1004-1009, 2000.
• Devamanoharan, P., et al. Prevention of lens protein glycation by taurine. Molecular and Cellular Biochemistry. 177(1-2): 245-250, 1997.
• Hammond Jr., B. and Johnson, M. The age-related eye disease study (AREDS). Nutrition Reviews. 60(9): 283-288, 2002.
• Hankinson, S., et al. Nutrient intake and cataract extraction in women: a prospective study. British Medical Journal. 305(6849): 335-339, 1992.
• Kassoff, A., et al. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8. Archives of Ophthalmology. 119(10): 1417-1436, 2001.
• Mares-Perlman, J., et al. Serum antioxidants and age-related macular degeneration in a population-based case-control study. Archives of Ophthalmology. 113(12): 1518-1523, 1995.
• Richer, S., et al. Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (Lutein Antioxidant Supplementation Trial). Optometry. 75(4): 216-230, 2004.
• Taren, D., et al. The night vision threshold test is a better predictor of low serum vitamin A concentration than self-reported night blindness in pregnant urban Nepalese women. Journal of Nutrition. 134(10): 2573-2578, 2004.
• Varma, S., et al. Diabetic cataracts and flavonoids. Science. 195(4274): 205-206, 1977.
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What Makes Isotonix® Vision Formula with Lutein Unique?*

Maintaining vision health is vital, especially during the aging process. When light is reflected off an object, the light waves from the object enter the eye through the cornea, which is the transparent front part of the eye that covers the iris, pupil and anterior chamber. The light is then filtered through to the pupil, which is the black circular or slit shaped opening in the center of the iris that regulates the amount of light that enters the eye. The iris is the colored portion of the eye that controls the pupil. The light then continues through the lens, located behind the iris and pupil, and made up of transparent proteins called crystallins. The light waves are bent or converged by the lens and the cornea to just behind the surface of the lens where it is then reversed and inverted.

The light waves then pass through the vitreous humor, the clear gel between the lens and the retina, which is a thin layer of neural cells that lines the back of the eyeball. The macula is a small, yellowish spot located in the middle of the retina that is responsible for the detail of vision by providing visual sharpness and color perception. The retina consists of a large number of photoreceptor cells, which contain a particular protein molecule called an opsin. In humans, there are two types of opsins: rod opsins and cone opsins. Each opsin absorbs a photon (a particle of light) and transmits a signal to the cell through a signal transduction pathway, resulting in hyper-polarization of the photoreceptor. Within the retina, light waves are changed into electrical signals and then sent through the optic nerve, along the visual pathway, to the occipital cortex at the posterior or back of the brain. The brain is what actually reconstructs or interprets the electrical impulses into a picture.

The intricate process that contributes to visual degradation usually develops over a long time-period, making the need for a protective eye approach even more important. Free radical activity is a constant factor in the body’s metabolism. Waiting to begin an antioxidant defense against oxidative stress until the prime senior years may be too late. Promoting visual health is important and can be accomplished through a healthy diet, exercise and the right supplementation.

Isotonix Vision Formula with Lutein is an isotonic-capable dietary supplement, combining vitamins and minerals with lutein, quercetin, eyebright, zeaxanthin and bilberry, designed to promote healthy vision throughout the aging process. Isotonix Vision Formula helps maintain the structural integrity of blood vessels and capillaries, helps maintain the membranes of cone cells in the eyes, helps maintain lens transparency, helps strengthen the cells of the retina, and promotes healthy oxygen and nutrient flow to the eyes. The antioxidant properties of Isotonix Vision Formula help protect the eyes from oxidative stress. It promotes healthy macular density, promotes healthy vision and supports night vision.

Isotonic, which means “same pressure,” bears the same chemical resemblance of the body’s blood, plasma and tears. All fluids in the body have a certain concentration, referred to as osmotic pressure. The body’s common osmotic pressure, which is isotonic, allows a consistent maintenance of body tissues. In order for a substance to be absorbed and used in the body’s metabolism, it must be transported in an isotonic state.

Isotonix dietary supplements are delivered in an isotonic solution. This means that the body has less work to do in obtaining maximum absorption. The isotonic state of the suspension allows nutrients to pass directly into the small intestine and be rapidly absorbed into the bloodstream. With Isotonix products, little nutritive value is lost, making the absorption of nutrients highly efficient while delivering maximum results.

Related terms: Isotonix® Vision Formula with Lutein, vision formula, lutein, isotonix, isotonic, macular degeneration, eye health, vision health, vision, macula.

Frequently Asked Questions about Isotonix® Vision Formula with Lutein*:

How does the Isotonix Vision Formula with Lutein work?

In the Age-Related Eye Disease Study, sponsored by the National Institute of Health, ingredients like those in Isotonix Vision Formula with Lutein were found to support eye health. The antioxidants in Isotonix Vision Formula with Lutein promote a healthy eye by neutralizing free radicals.

How is the Isotonix Vision Formula with Lutein different from other vision formulas?

Isotonix Vision Formula with Lutein contains 14 of the known essential vitamins and minerals that contribute to overall vision health. Additionally, it is isotonic form, which contributes to maximum absorption by the body.

What if I am taking a prescription; is Isotonix Vision Formula with Lutein safe?

While all of the ingredients in Isotonix Vision Formula are found in nature and unlikely to interfere with any prescription, it would be wise to contact your physician before including this or any other dietary supplement in your nutritional regimen.

What studies have been done to show that the ingredients in Isotonix Vision Formula with Lutein are effective?

Studies show that the carotenoids: lutein, zeazanthin and B-C will help support eye health. According to the results of a government study led in part by researchers at Johns Hopkin’s Wilmer Eye Institute, if those who were at risk for vision degradation chose to use daily supplements of antioxidant vitamins and zinc, the risk of vision loss for more than 300,000 people could be avoided over the next five years.

In October 2001, the National Eye Institute published the results of a seven-year study called the Age-Related Eye Disease Study (AREDS). The study showed that a high dose combination of vitamin C, vitamin E, beta-carotene and zinc could significantly reduce the risk of certain factors leading to visual degradation by about 25 percent. A nutritional supplement featuring this unique combination could allow you to enjoy quality of eyesight into your golden years.

How many people are affected with vision loss?

It is estimated that 300,000 Americans are blind and nearly 13 million have partial vision loss due to poor eye health. Age-related macular degeneration is the leading cause of blindness in Americans ages 65 and older.

Is it ok for me to take additional vitamins?

Yes. Isotonix Vision Formula with Lutein pairs well with Isotonix® Multivitamin, Isotonix® Multi-Mineral and other great Market America vitamin and mineral products.

What is an antioxidant?

Antioxidants act as cell protectors by neutralizing free radicals. Free radicals are harmful byproducts that can cause cellular damage that can lead to serious health problems. Free radicals cause oxidative damage to the body, meaning premature aging, hardening of the arteries, stiffened joints and wrinkling of the skin. Air pollution, heavy exercise, stress and smoking can all contribute to creating harmful free radicals.