Bliss™ Anti-Stress Formula - Single Bottle (30 Servings)

Primary Benefits of Bliss™ Anti-Stress Formula:

·         Promotes relaxation without drowsiness

·         Helps maintain healthy levels of both serotonin and dopamine

·         Helps enhance and stabilize mood

·         Helps the body adapt to stress

·         Increases mental clarity

Key Ingredients Found In Bliss™ Anti-Stress Formula:

L-Theanine
Theanine is the major amino acid found in green tea. It has historically been used for its relaxing effects. It is believed that theanine may work for relaxation by promoting normal levels of GABA (Gamma Amino Butyric Acid) and serotonin. In the central nervous system, GABA is the primary inhibitory neurotransmitter. It is synthesized in the brain by the decarboxylation of glutamate. GABA exerts anticonvulsant, sedative and anxiolytic effects at the cellular level.

Rhodiola
Roseroot contains a phenylpropanoid glycoside called salidroside. This constituent is also sometimes referred to as rhodioloside or rhodosine. This constituent is thought to be responsible for roseroot's relaxation and adaptogenic actions (increasing resistance to the harmful effects of stressors). Animal studies have shown protection from stressors, increased work capacity and decreased fatigue. Roseroot extracts also demonstrate potential for supporting learning and memory.
   
Ashwagandha
Ashwagandha is an Indian herb known as Winter Cherry. It tends to be classified as an Indian ginseng. Some research suggests ashwagandha may have a relaxing effect. Preliminary evidence suggests ashwagandha might  promote normal levels of dopamine receptors in the corpus striatum of the brain. It also appears to promote normal levels of plasma corticosterone, blood urea nitrogen and blood lactic acid.

Eleuthero, Siberian Ginseng
Siberian Ginseng was discovered in the former northern Soviet Union. It was found to enhance athletic performance and help the body adapt to stress. Eleuthero has been shown to enhance mental acuity without the letdown that comes with caffeinated products. Siberian Ginseng is an adaptogen which has a homeostatic or “balancing” effect on the body. Adaptogens help the body deal with stressful conditions, because of its homeostatic properties. It is thought to help support adrenal gland function when the body is challenged by stress. In addition to its effect on stress, Eleuthero increases cognitive function.

Passion Flower
Passion flower is the perennial blossoming vine that is native to the southeastern United States, Brazil and Argentina. Its medicinal properties come from its above ground part. Passion flower has sedative effects. Some evidence suggests the passion flower constituent apigenin binds to central benzodiazepine receptors, possibly causing relaxation without impairing memory or motor skills. Some studies have pointed to the flavonoids in passion flower as the primary constituents responsible for its relaxing effects. It is thought that passion flower may enhance the effectiveness of other anxiety treatments.

Bacopa
Some evidence suggests purified bacosides A and B may facilitate learning ability and cognitive performance. Possible mechanisms for cognitive improvement include supporting normal acetylcholine release, choline acetylase activity and muscarinic cholinergic receptor binding.

Scientific Studies Which Support Bliss™ Anti-Stress Formula:

·         Akhondzadeh, S., et al.  Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxezepam.  J Clin Pharm Ther.  26(5):363-367, 2001.

·         Archana, R., et al.  Antistressor effect of Withania somnifera.  Journal of Ethnopharmacology.  64(1):91-93, 1999.

·         Bacopa monniera. Monograph. Altern Med Rev 9(1):79-85, 2004. Review.

·         Bhattacharya, S. K., et al.  Adaptogenic activity of Withania somnifera: an experimental study using a rat model of chronic stress.  Pharmacol Biochem Behav.  75(3):547-555, 2003.

·         Bhattacharya, S. K., et al.  Anxiolytic-antidepressant activity of Withania somnifera glycowithanolides: an experimental study.  Phytomedicine.  7(6):463-469, 2000.

·         Davydov M and Krikorian AD. Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. (Araliaceae) as an adaptogen: a closer look. J Ethnopharmacol 72:345-93, 2000.

·         Dhawan, K., et al.  Anti-anxiety studies on extracts of Passiflora incarnata Linneaus.  J Ethnopharmacol.  78(2-3):165-170, 2001.

·         Dhuley, J. N.  Effect of ashwagandha on lipid peroxidation in stress-induced animals.  J Ethnopharmacol.  60(2):173-178, 1998.

·         Dhuley, JN. Adaptogenic and cardioprotective action of ashwagandha in rats and frogs. J Ethnopharmacol 70(1):57-63, 2000.

·         Dufresne, CJ and Farnworth ER. A review of latest research findings on the health promotion properties of tea. The Journal of Nutritional Biochemistry 12(7): 404-21, 2001.

·         Gaffney, B. T., et al.  Panax ginseng and Eleutherococcus senticosus may exaggerate an already existing biphasic response to stress via inhibition of enzymes which limit the binding of stress hormones to their receptors.  Medical Hypotheses.  56(5):567-572, 2001.

·         Grandhi A. A comparative pharmacological investigation of Ashwagandha and Ginseng. J Ethnopharmacol 44(3):131-5, 1994.

·         Ito, K., et al.  Effects of L-theanine on the release of alpha brain waves in human volunteers.  Nippon Nogeikagaku Kaishi 72:153-157, 1998.

·         Kelly, G. Nutritional and botanical interventions to assist with the adaptation to stress. Alt Med Review 4: 249-265, 1999.

·         Kelly, G. Rhodiola rosea: a possible plant adaptogen. Altern Med Rev 6(3):293-302., 2001. Review.

·         L-Theanine Monograph.  Alternative Medicine Review 2005;10(2):136-138.

·         Lu, K., et al. The acute effects of L-theanine in comparison with alprazolam on anticipatory anxiety in humans. Hum Psychopharmacol 19(7):457-65, 2004.

·         Mishra LC, Singh BB, Dagenais S. Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review. Altern Med Rev 5:334-46, 2000.

·         Rai, D. Adaptogenic effect of Bacopa monniera (Brahmi). Pharmacol Biochem Behav 75(4):823-30, 2003.

·         Rhodiola Monograph. Altern Med Rev 7(5):421-3, 2002.

·         Russo A, Borrelli F.  Bacopa monniera, a reputed nootropic plant: an overview.  Phytomedicine 2005;12:305-317. 

·         Sairam K., et al. Antidepressant activity of standardized extract of Bacopa monniera in experimental models of depression in rats. Phytomedicine 9(3):207-11, 2002.

·         Spasov, A. A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen. Phytomedicine 7(2):85-9, 2000.

·         Withania somnifera (Ashwagandha) Monograph. Altern Med Rev 9(2): 211-214, 2004.

What Makes Bliss™ Anti-Stress Formula Unique?

No matter how well we eat, how often we exercise or how hard we try to avoid certain situations, we can’t escape stress. Stress affects all of us. It clouds our mind and compromises our judgment. Stress has negative effects on our bodies, from tense muscles to an overall diminished sense of well being. Feeding your mind and boosting your energy level can do wonders in your quest to look good, feel good and enjoy life. Bliss Anti-Stress Formula promotes relaxation without drowsiness, helps stabilize your mood, and is ideal for any individual encountering consistently stressful days or an upcoming stressful event.

Bliss Anti-Stress Formula helps you relax without making you sleepy. It is specially formulated with Siberian Ginseng and Ashwagandha, which have been shown to help the body adapt to stress. It may also help to improve your cognitive performance by increasing your mental clarity. It helps the body adapt to stress naturally. Bliss Anti-Stress is perfect for those stressful days or situations that you can’t avoid. So relax, enjoy life, and give your body the gift of Bliss Anti-Stress Formula!

Frequently Asked Questions About Bliss™ Anti-Stress Formula:

How should I take this product?
Take two per day. You may take one pill or both pills at the same time depending on your preference.

What other nutritional supplements could augment the biological effects of this product?
Isotonix® Advanced B-Complex and Isotonix Multivitamin

What are the contraindications for this supplement?
If you are currently taking warfarin (Coumadin), other anti-platelet/anti-coagulant medications, antihypertensive medications, anti-depressants, anti-anxiety medications or have an ongoing medical condition, you should consult your physician before using this product. Women who are pregnant or nursing should not use this product. This product may decrease the effects of stimulants and caffeine.

How does it relax without making you tired?
The Siberian Ginseng and the Ashwagandha are natural stimulants. They reduce your stress levels but aren’t formulated to make you drowsy. Ginseng acts in a way similar to caffeine but doesn’t make you jittery and won’t deplete your energy.

Can I take Bliss Anti-Stress Formula instead of my prescription?
No. Bliss Anti-Stress is not intended to replace prescription drugs. Bliss Anti-Stress is a natural reliever of sudden stress. It is intended for use during or after engaging in stressful activities. You should contact your doctor before going off any prescriptions.

If I am on a prescription for anxiety, is it safe to use Bliss Anti-Stress Formula?
It would be wise to consult your doctor before adding any dietary supplement. The ingredients in Bliss Anti-Stress are all found in nature, they may have side effects, so make sure to contact your doctor or pharmacist before mixing them.

Primary Benefits of Bliss™ Anti-Stress Formula:

·         Promotes relaxation without drowsiness

·         Helps maintain healthy levels of both serotonin and dopamine

·         Helps enhance and stabilize mood

·         Helps the body adapt to stress

·         Increases mental clarity

Key Ingredients Found In Bliss™ Anti-Stress Formula:

L-Theanine
Theanine is the major amino acid found in green tea. It has historically been used for its relaxing effects. It is believed that theanine may work for relaxation by promoting normal levels of GABA (Gamma Amino Butyric Acid) and serotonin. In the central nervous system, GABA is the primary inhibitory neurotransmitter. It is synthesized in the brain by the decarboxylation of glutamate. GABA exerts anticonvulsant, sedative and anxiolytic effects at the cellular level.

Rhodiola
Roseroot contains a phenylpropanoid glycoside called salidroside. This constituent is also sometimes referred to as rhodioloside or rhodosine. This constituent is thought to be responsible for roseroot's relaxation and adaptogenic actions (increasing resistance to the harmful effects of stressors). Animal studies have shown protection from stressors, increased work capacity and decreased fatigue. Roseroot extracts also demonstrate potential for supporting learning and memory.
   
Ashwagandha
Ashwagandha is an Indian herb known as Winter Cherry. It tends to be classified as an Indian ginseng. Some research suggests ashwagandha may have a relaxing effect. Preliminary evidence suggests ashwagandha might  promote normal levels of dopamine receptors in the corpus striatum of the brain. It also appears to promote normal levels of plasma corticosterone, blood urea nitrogen and blood lactic acid.

Eleuthero, Siberian Ginseng
Siberian Ginseng was discovered in the former northern Soviet Union. It was found to enhance athletic performance and help the body adapt to stress. Eleuthero has been shown to enhance mental acuity without the letdown that comes with caffeinated products. Siberian Ginseng is an adaptogen which has a homeostatic or “balancing” effect on the body. Adaptogens help the body deal with stressful conditions, because of its homeostatic properties. It is thought to help support adrenal gland function when the body is challenged by stress. In addition to its effect on stress, Eleuthero increases cognitive function.

Passion Flower
Passion flower is the perennial blossoming vine that is native to the southeastern United States, Brazil and Argentina. Its medicinal properties come from its above ground part. Passion flower has sedative effects. Some evidence suggests the passion flower constituent apigenin binds to central benzodiazepine receptors, possibly causing relaxation without impairing memory or motor skills. Some studies have pointed to the flavonoids in passion flower as the primary constituents responsible for its relaxing effects. It is thought that passion flower may enhance the effectiveness of other anxiety treatments.

Bacopa
Some evidence suggests purified bacosides A and B may facilitate learning ability and cognitive performance. Possible mechanisms for cognitive improvement include supporting normal acetylcholine release, choline acetylase activity and muscarinic cholinergic receptor binding.

Scientific Studies Which Support Bliss™ Anti-Stress Formula:

·         Akhondzadeh, S., et al.  Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxezepam.  J Clin Pharm Ther.  26(5):363-367, 2001.

·         Archana, R., et al.  Antistressor effect of Withania somnifera.  Journal of Ethnopharmacology.  64(1):91-93, 1999.

·         Bacopa monniera. Monograph. Altern Med Rev 9(1):79-85, 2004. Review.

·         Bhattacharya, S. K., et al.  Adaptogenic activity of Withania somnifera: an experimental study using a rat model of chronic stress.  Pharmacol Biochem Behav.  75(3):547-555, 2003.

·         Bhattacharya, S. K., et al.  Anxiolytic-antidepressant activity of Withania somnifera glycowithanolides: an experimental study.  Phytomedicine.  7(6):463-469, 2000.

·         Davydov M and Krikorian AD. Eleutherococcus senticosus (Rupr. & Maxim.) Maxim. (Araliaceae) as an adaptogen: a closer look. J Ethnopharmacol 72:345-93, 2000.

·         Dhawan, K., et al.  Anti-anxiety studies on extracts of Passiflora incarnata Linneaus.  J Ethnopharmacol.  78(2-3):165-170, 2001.

·         Dhuley, J. N.  Effect of ashwagandha on lipid peroxidation in stress-induced animals.  J Ethnopharmacol.  60(2):173-178, 1998.

·         Dhuley, JN. Adaptogenic and cardioprotective action of ashwagandha in rats and frogs. J Ethnopharmacol 70(1):57-63, 2000.

·         Dufresne, CJ and Farnworth ER. A review of latest research findings on the health promotion properties of tea. The Journal of Nutritional Biochemistry 12(7): 404-21, 2001.

·         Gaffney, B. T., et al.  Panax ginseng and Eleutherococcus senticosus may exaggerate an already existing biphasic response to stress via inhibition of enzymes which limit the binding of stress hormones to their receptors.  Medical Hypotheses.  56(5):567-572, 2001.

·         Grandhi A. A comparative pharmacological investigation of Ashwagandha and Ginseng. J Ethnopharmacol 44(3):131-5, 1994.

·         Ito, K., et al.  Effects of L-theanine on the release of alpha brain waves in human volunteers.  Nippon Nogeikagaku Kaishi 72:153-157, 1998.

·         Kelly, G. Nutritional and botanical interventions to assist with the adaptation to stress. Alt Med Review 4: 249-265, 1999.

·         Kelly, G. Rhodiola rosea: a possible plant adaptogen. Altern Med Rev 6(3):293-302., 2001. Review.

·         L-Theanine Monograph.  Alternative Medicine Review 2005;10(2):136-138.

·         Lu, K., et al. The acute effects of L-theanine in comparison with alprazolam on anticipatory anxiety in humans. Hum Psychopharmacol 19(7):457-65, 2004.

·         Mishra LC, Singh BB, Dagenais S. Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review. Altern Med Rev 5:334-46, 2000.

·         Rai, D. Adaptogenic effect of Bacopa monniera (Brahmi). Pharmacol Biochem Behav 75(4):823-30, 2003.

·         Rhodiola Monograph. Altern Med Rev 7(5):421-3, 2002.

·         Russo A, Borrelli F.  Bacopa monniera, a reputed nootropic plant: an overview.  Phytomedicine 2005;12:305-317. 

·         Sairam K., et al. Antidepressant activity of standardized extract of Bacopa monniera in experimental models of depression in rats. Phytomedicine 9(3):207-11, 2002.

·         Spasov, A. A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen. Phytomedicine 7(2):85-9, 2000.

·         Withania somnifera (Ashwagandha) Monograph. Altern Med Rev 9(2): 211-214, 2004.

What Makes Bliss™ Anti-Stress Formula Unique?

No matter how well we eat, how often we exercise or how hard we try to avoid certain situations, we can’t escape stress. Stress affects all of us. It clouds our mind and compromises our judgment. Stress has negative effects on our bodies, from tense muscles to an overall diminished sense of well being. Feeding your mind and boosting your energy level can do wonders in your quest to look good, feel good and enjoy life. Bliss Anti-Stress Formula promotes relaxation without drowsiness, helps stabilize your mood, and is ideal for any individual encountering consistently stressful days or an upcoming stressful event.

Bliss Anti-Stress Formula helps you relax without making you sleepy. It is specially formulated with Siberian Ginseng and Ashwagandha, which have been shown to help the body adapt to stress. It may also help to improve your cognitive performance by increasing your mental clarity. It helps the body adapt to stress naturally. Bliss Anti-Stress is perfect for those stressful days or situations that you can’t avoid. So relax, enjoy life, and give your body the gift of Bliss Anti-Stress Formula!

Frequently Asked Questions About Bliss™ Anti-Stress Formula:

How should I take this product?
Take two per day. You may take one pill or both pills at the same time depending on your preference.

What other nutritional supplements could augment the biological effects of this product?
Isotonix® Advanced B-Complex and Isotonix Multivitamin

What are the contraindications for this supplement?
If you are currently taking warfarin (Coumadin), other anti-platelet/anti-coagulant medications, antihypertensive medications, anti-depressants, anti-anxiety medications or have an ongoing medical condition, you should consult your physician before using this product. Women who are pregnant or nursing should not use this product. This product may decrease the effects of stimulants and caffeine.

How does it relax without making you tired?
The Siberian Ginseng and the Ashwagandha are natural stimulants. They reduce your stress levels but aren’t formulated to make you drowsy. Ginseng acts in a way similar to caffeine but doesn’t make you jittery and won’t deplete your energy.

Can I take Bliss Anti-Stress Formula instead of my prescription?
No. Bliss Anti-Stress is not intended to replace prescription drugs. Bliss Anti-Stress is a natural reliever of sudden stress. It is intended for use during or after engaging in stressful activities. You should contact your doctor before going off any prescriptions.

If I am on a prescription for anxiety, is it safe to use Bliss Anti-Stress Formula?
It would be wise to consult your doctor before adding any dietary supplement. The ingredients in Bliss Anti-Stress are all found in nature, they may have side effects, so make sure to contact your doctor or pharmacist before mixing them.