headrest™ Head Comfort Formula

Primary Benefits of Headrest™ Head Comfort Formula*:

• Helps maintain optimal blood flow to the brain
• Helps the body maintain a healthy (or sufficient or proper) level of magnesium, which correlates with brain health
• Helps to maintain brain health
• In clinical trials in both Germany and the United States, butterbur reduced the incidence of head cavity discomforts by up to 61 percent
• Magnesium deficiency is common among head discomfort sufferers
• Promotes normal sinus function
• Promotes proper blood circulation in the brain which helps to maintain head comfort (or which works to support head comfort)
• Supports/promotes head comfort (reduces the frequency, severity, and duration of head discomfort)
• Supports/Promotes healthy cognitive function
• Supports/promotes healthy platelet activity and blood vessel dilation (inhibits serotonin release from platelets and leucocytes)
• Supports/Promotes healthy respiratory functions
• Supports a healthy immune system

Key Ingredients Found In Headrest™ Head Comfort Formula:

Riboflavin (Vitamin B2): 25 mg

Riboflavin is a catalyst in metabolic function. Its primary activity is to help convert food into energy, but it also promotes normal blood cell formation and proper nervous system function. Riboflavin can be found in green vegetables, liver, seafood and dairy products. It is a key ingredient in many multivitamins and B-complexes. It works by helping to support the languid cellular energy system to placate the head discomfort.*

Magnesium (Magnesium oxide and magnesium citrate): 600 mg

Magnesium promotes the conversion of carbohydrates, proteins and fat into energy. It can be found in foods like artichokes, nuts, beans, whole grains and shellfish. Taking a large serving of magnesium citrate or trimagnesium dicitrate orally seems to reduce the frequency and severity of head discomfort. A deficiency or low intake of magnesium is common among head discomfort sufferers.  Stuides have shown that if people increased their intake of magnesium they might reduce the frequency of head discomfort.*

Feverfew Leaf Extract (0.2% parthenolide): 125 mg

Feverfew usage originated in southeastern Europe and spread throughout Europe, Australia and North America. Only the leaves are used in herbal supplements.  Traditionally it has been used as a general wellness tonic and to relax and enhance mood.  Today it is used for a variety of other purposes, including the promotion of head comfort.  Evidence has shown that taking feverfew orally can reduce the frequency of head discomfort.  It's unclear exactly how feverfew works in the promotion of head comfort but some laboratory evidence suggests that feverfew extracts might promote normal platelet activity and support normal serotonin levels. Feverfew seems to work as a maintenance step in promoting head comfort.*  

Butterbur Root Extract (Petasites hybridus) (15% petasin, petasol, neopetasol, and isopetasin): 50 mg

Butterbur comes from the Petasite plant, which is found throughout Asia, Europe and some parts of North America.  Studies have shown that butterbur can reduce the frequency, intensity and duration of head discomfort when used over a period of a few months.  Butterbur works in conjuction with other herbs and nutrients to optimize consistent head comfort.  In clinical trials in both Germany and the United States, butterbur reduced the incidence of head discomfort by up to 61 percent.*

Scientific Studies Which Support headrest™ Head Comfort Formula:

·         Boehnke, C., et al.  High-dose riboflavin treatment is efficacious in migraine prophylaxis: an open study in a tertiary care centre.  Eur J Neurol 11(7):475-477, 2004.

·         Breen C., et al. High-dose riboflavin for prophylaxis of migraine. Can Fam Physician 49:1291-3, 2003.

·         Brown R. and Gerbarg P. Herbs and nutrients in the treatment of depression, anxiety, insomnia, migraine, and obesity. J Psychiatr Pract. 7(2):75-91, 2001.

·         Danesch UC. Petasites hybridus (Butterbur root) extract in the treatment of asthma--an open trial. Altern Med Rev. 9(1):54-62, 2004.

·         Danesch, U., et al.  Safety of a patented special butterbur root extract for migraine prevention.  Headache.  43(1):76-78, 2003.

·         Diener H., et al. Efficacy and safety of 6.25 mg t.i.d. feverfew CO2-extract (MIG-99) in migraine prevention--a randomized, double-blind, multicentre, placebo-controlled study. Cephalalgia. 25(11):1031-41, 2005.

·         Diener, H. C., et al.  The first placebo-controlled trial of a special butterbur root extract for the prevention of migraine: reanalysis of efficacy criteria.  Eur Neurol.  51(2):89-97, 2004.

·         Groenewegen W. and Heptinstall S. A comparison of the effects of an extract of feverfew and parthenolide, a component of feverfew, on human platelet activity in-vitro. J Pharm Pharmacol. 42(8):553-7, 1990.

·         Grossman, W., et al.  An extract of Petasites hybridus is effective in the prophylaxis of migraine.  Alternative Medicine Review.  6(3):303-310, 2001.

·         Heptinstall, S., et al. Extracts of feverfew may inhibit platelet behaviour via neutralization of sulphydryl groups. J Pharm Pharmacol. 39(6):459-65, 1987.

·         Knapp, H. Reduced allergen-induced nasal congestion and leukotriene synthesis with an orally active 5-lipoxygenase inhibitor. N Engl J Med. 323(25):1745-8, 1990.

·         Lipton, R. B., et al.  Petasites hybridus root (butterbur) is an effective preventive treatment for migraine.  Neurology.  63(12):2240-2244, 2004.

·         Maizels, M., et al. A combination of riboflavin, magnesium, and feverfew for migraine prophylaxis: a randomized trial. Headache. 44(9):885-90, 2004.

·         Mauskop, A., et al.  Role of magnesium in the pathogenesis and treatment of migraines.  Clin Neurosci.  5(1):24-27, 1998.

·         Mazzotta, G., et al.  Electromyographical ischemic test and intracellular and extracellular magnesium concentration in migraine and tension-type headache patients.  Headache.  36(6):357-361, 1996.

·         McCarty, M. Magnesium taurate and fish oil for prevention of migraine. Med Hypotheses. 47(6):461-6, 1996. Review.

·         Monograph:  Petasites hybridus (Butterbur).  Alternative Medicine Review.  6(2): 207, 2001.

·         Murphy, J. J., et al.  Randomized double-blind placebo-controlled trial of feverfew in migraine prevention.  Lancet.  2:189-192, 1988.

·         O’hara M., et al. A review of 12 commonly used medicinal herbs. Arch Fam Med 7(6):523-36, 1998. Review.

·         Peikert, A., et al.  Prophylaxis of migraine with oral magnesium:  Results from a prospective, multi-center, placebo-controlled and double-blind randomized study.  Cephalalgia. 16(4):257-63, 1996.

·         Pothmann, M., et al. Migraine prevention in children and adolescents: results of an open study with a special butterbur root extract. Headache. 45(3):196-203, 2005.

·         Schapowal, A. Randomised controlled trial of butterbur and cetirizine for treating seasonal allergic rhinitis. BMJ. 324(7330):144-6, 2002.

·         Schapowal, A. Treating intermittent allergic rhinitis: a prospective, randomized, placebo and antihistamine-controlled study of Butterbur extract Ze 339. Phytother Res.19(6):530-7, 2005.

·         Schoenen, J., et al.  Effectiveness of high-dose riboflavin in migraine prophylaxis.  A randomized controlled trial.  Neurology.  50:466-470, 1998.

·         Schoenen, J., et al.  High dose riboflavin as a prophylactic treatment of migraine: results of an open pilot study.  Cephalalgia.  14:328-329, 1994.

·         Sinclair, S., et al.  Migraine headaches: nutritional, botanical and other alternative approaches.  Alternative Medicine Review.  4(2):86-95, 1999.

·         Thomet, O. and Simon, H. Petasins in the treatment of allergic diseases: results of preclinical and clinical studies. Int Arch Allergy Immunol. 129(2):108-12, 2002.

·         Trauninger, A., et al.  Oral magnesium load test in patients with migraine.  Headache.  42(4):114-119, 2002.

·         Vogler B., et al. Feverfew as a preventive treatment for migraine: a systematic review. Cephalalgia. 18(10):704-8, 1998.  Review.

·         Wang, F., et al.  Oral magnesium oxide prophylaxis of frequent migrainous headache in children: a randomized, double-blind, placebo-controlled trial.  Headache.  43(6):601-610, 2003.

·         Welch, K. M., et al.  Mitochondria, magnesium and migraine.  J Neurol Sci.  134(1-2):9-14, 1995.

·         Woolhouse, M. Migraine and tension headache--a complementary and alternative medicine approach. Aust Fam Physician. 34(8):647-51, 2005.  Review.

What Makes Headrest™ Head Comfort Formula Unique?

People who are prone to head discomfort have different brain chemistry from those who rarely experience any head discomfort.  Sometimes the severity of head discomfort is not fully realized until it results in nausea, vomiting, sensitivity to light, noise or smells. For this reason, it is extremely important for those who often experience head discomfort to take regular steps to maintain head comfort. Two ways to help maintain head comfort are to maintain normal serotonin, which is a messenger that helps regulate the diameter of the blood vessels.  Fluctuations in serotonin cause the blood vessels in the brain to frequently expand and contract   causing discomfort. Another way to maintain head comfort is to help your body maintain proper circulation. 

Headrest™ Head Comfort Formula is specially formulated with Riboflavin (vitamin B2), magnesium, feverfew and butterbur, which work synergistically to help the body maintain healthy platelet activity thereby, reducing the frequency, severity and duration of head discomfort. Headrest helps maintain optimal blood flow to the brain, promotes normal sinus function, supports healthy blood vessel dilation, promotes healthy respiratory functions, which all help to maintain head comfort or work to support head comfort. In clinical trials in both Germany and the U.S., butterbur reduced the incidence of head cavity discomfort by up to 61 percent. Headrest supplies a healthy level of magnesium, which correlates with brain health (magnesium deficiency is common among head discomfort sufferers). In addition to promoting head comfort, Headrest supports a healthy immune system and promotes healthy cognitive function.*

Frequently Asked Questions About Headrest™ Head Comfort Formula:

Does Headrest™ contain caffeine?

No, Headrest does not contain caffeine.

Will taking Headrest make me drowsy?

Butterbur has the potential to cause drowsiness, but generally Headrest should be well tolerated.

What does PA Free mean and why is this important?

Pyrrolizidine alkaloid (PA) constituents are present in butterbur and have been shown to be hepatotoxic (liver toxic). The butterbur extract used in Headrest is PA-free and clear of all hepatotoxins.

How should I take Headrest?

HeadRest should be taken daily, in order to maintain head comfort. 

Who will benefit from Headrest?

Those who experience head discomfort.

What other Market America Products would compliment Headrest?

Isotonix^® Coenzyme Q10, Isotonix B-Complex, Isotonix Maximum ORAC, Isotonix MultiTech

Are there any warnings or contraindications for Headrest?

Yes. If you are currently taking diuretics, Cimetidine (anti-ulcer histamine blocker), antibiotics, warfarin (Coumadin), other anti-platelet/anti-coagulant medications, hydroxycholoroquine (antimalarial), corticosteroids, risedronate or other bisphosphonates, you should not take this product. Due to the magnesium content, you should not take this product if you have kidney failure. Feverfew may cause an allergic reaction in individuals sensitive to ragweed, chrysanthemums, marigolds or daisies. If you are taking any other prescription drugs or have an ongoing medical condition, you should consult your physician before using this product.  Women who are pregnant or nursing should not take this product.

How does this support normal sinus function?

Petasins, found in butterbur, have been shown to promote normal levels nasal inflammatory mediators associated with normal sinus function.

How do I take Headrest?

Take two capsules daily with food.

Primary Benefits of Headrest™ Head Comfort Formula*:

• Helps maintain optimal blood flow to the brain
• Helps the body maintain a healthy (or sufficient or proper) level of magnesium, which correlates with brain health
• Helps to maintain brain health
• In clinical trials in both Germany and the United States, butterbur reduced the incidence of head cavity discomforts by up to 61 percent
• Magnesium deficiency is common among head discomfort sufferers
• Promotes normal sinus function
• Promotes proper blood circulation in the brain which helps to maintain head comfort (or which works to support head comfort)
• Supports/promotes head comfort (reduces the frequency, severity, and duration of head discomfort)
• Supports/Promotes healthy cognitive function
• Supports/promotes healthy platelet activity and blood vessel dilation (inhibits serotonin release from platelets and leucocytes)
• Supports/Promotes healthy respiratory functions
• Supports a healthy immune system

Key Ingredients Found In Headrest™ Head Comfort Formula:

Riboflavin (Vitamin B2): 25 mg

Riboflavin is a catalyst in metabolic function. Its primary activity is to help convert food into energy, but it also promotes normal blood cell formation and proper nervous system function. Riboflavin can be found in green vegetables, liver, seafood and dairy products. It is a key ingredient in many multivitamins and B-complexes. It works by helping to support the languid cellular energy system to placate the head discomfort.*

Magnesium (Magnesium oxide and magnesium citrate): 600 mg

Magnesium promotes the conversion of carbohydrates, proteins and fat into energy. It can be found in foods like artichokes, nuts, beans, whole grains and shellfish. Taking a large serving of magnesium citrate or trimagnesium dicitrate orally seems to reduce the frequency and severity of head discomfort. A deficiency or low intake of magnesium is common among head discomfort sufferers.  Stuides have shown that if people increased their intake of magnesium they might reduce the frequency of head discomfort.*

Feverfew Leaf Extract (0.2% parthenolide): 125 mg

Feverfew usage originated in southeastern Europe and spread throughout Europe, Australia and North America. Only the leaves are used in herbal supplements.  Traditionally it has been used as a general wellness tonic and to relax and enhance mood.  Today it is used for a variety of other purposes, including the promotion of head comfort.  Evidence has shown that taking feverfew orally can reduce the frequency of head discomfort.  It's unclear exactly how feverfew works in the promotion of head comfort but some laboratory evidence suggests that feverfew extracts might promote normal platelet activity and support normal serotonin levels. Feverfew seems to work as a maintenance step in promoting head comfort.*  

Butterbur Root Extract (Petasites hybridus) (15% petasin, petasol, neopetasol, and isopetasin): 50 mg

Butterbur comes from the Petasite plant, which is found throughout Asia, Europe and some parts of North America.  Studies have shown that butterbur can reduce the frequency, intensity and duration of head discomfort when used over a period of a few months.  Butterbur works in conjuction with other herbs and nutrients to optimize consistent head comfort.  In clinical trials in both Germany and the United States, butterbur reduced the incidence of head discomfort by up to 61 percent.*

Scientific Studies Which Support headrest™ Head Comfort Formula:

·         Boehnke, C., et al.  High-dose riboflavin treatment is efficacious in migraine prophylaxis: an open study in a tertiary care centre.  Eur J Neurol 11(7):475-477, 2004.

·         Breen C., et al. High-dose riboflavin for prophylaxis of migraine. Can Fam Physician 49:1291-3, 2003.

·         Brown R. and Gerbarg P. Herbs and nutrients in the treatment of depression, anxiety, insomnia, migraine, and obesity. J Psychiatr Pract. 7(2):75-91, 2001.

·         Danesch UC. Petasites hybridus (Butterbur root) extract in the treatment of asthma--an open trial. Altern Med Rev. 9(1):54-62, 2004.

·         Danesch, U., et al.  Safety of a patented special butterbur root extract for migraine prevention.  Headache.  43(1):76-78, 2003.

·         Diener H., et al. Efficacy and safety of 6.25 mg t.i.d. feverfew CO2-extract (MIG-99) in migraine prevention--a randomized, double-blind, multicentre, placebo-controlled study. Cephalalgia. 25(11):1031-41, 2005.

·         Diener, H. C., et al.  The first placebo-controlled trial of a special butterbur root extract for the prevention of migraine: reanalysis of efficacy criteria.  Eur Neurol.  51(2):89-97, 2004.

·         Groenewegen W. and Heptinstall S. A comparison of the effects of an extract of feverfew and parthenolide, a component of feverfew, on human platelet activity in-vitro. J Pharm Pharmacol. 42(8):553-7, 1990.

·         Grossman, W., et al.  An extract of Petasites hybridus is effective in the prophylaxis of migraine.  Alternative Medicine Review.  6(3):303-310, 2001.

·         Heptinstall, S., et al. Extracts of feverfew may inhibit platelet behaviour via neutralization of sulphydryl groups. J Pharm Pharmacol. 39(6):459-65, 1987.

·         Knapp, H. Reduced allergen-induced nasal congestion and leukotriene synthesis with an orally active 5-lipoxygenase inhibitor. N Engl J Med. 323(25):1745-8, 1990.

·         Lipton, R. B., et al.  Petasites hybridus root (butterbur) is an effective preventive treatment for migraine.  Neurology.  63(12):2240-2244, 2004.

·         Maizels, M., et al. A combination of riboflavin, magnesium, and feverfew for migraine prophylaxis: a randomized trial. Headache. 44(9):885-90, 2004.

·         Mauskop, A., et al.  Role of magnesium in the pathogenesis and treatment of migraines.  Clin Neurosci.  5(1):24-27, 1998.

·         Mazzotta, G., et al.  Electromyographical ischemic test and intracellular and extracellular magnesium concentration in migraine and tension-type headache patients.  Headache.  36(6):357-361, 1996.

·         McCarty, M. Magnesium taurate and fish oil for prevention of migraine. Med Hypotheses. 47(6):461-6, 1996. Review.

·         Monograph:  Petasites hybridus (Butterbur).  Alternative Medicine Review.  6(2): 207, 2001.

·         Murphy, J. J., et al.  Randomized double-blind placebo-controlled trial of feverfew in migraine prevention.  Lancet.  2:189-192, 1988.

·         O’hara M., et al. A review of 12 commonly used medicinal herbs. Arch Fam Med 7(6):523-36, 1998. Review.

·         Peikert, A., et al.  Prophylaxis of migraine with oral magnesium:  Results from a prospective, multi-center, placebo-controlled and double-blind randomized study.  Cephalalgia. 16(4):257-63, 1996.

·         Pothmann, M., et al. Migraine prevention in children and adolescents: results of an open study with a special butterbur root extract. Headache. 45(3):196-203, 2005.

·         Schapowal, A. Randomised controlled trial of butterbur and cetirizine for treating seasonal allergic rhinitis. BMJ. 324(7330):144-6, 2002.

·         Schapowal, A. Treating intermittent allergic rhinitis: a prospective, randomized, placebo and antihistamine-controlled study of Butterbur extract Ze 339. Phytother Res.19(6):530-7, 2005.

·         Schoenen, J., et al.  Effectiveness of high-dose riboflavin in migraine prophylaxis.  A randomized controlled trial.  Neurology.  50:466-470, 1998.

·         Schoenen, J., et al.  High dose riboflavin as a prophylactic treatment of migraine: results of an open pilot study.  Cephalalgia.  14:328-329, 1994.

·         Sinclair, S., et al.  Migraine headaches: nutritional, botanical and other alternative approaches.  Alternative Medicine Review.  4(2):86-95, 1999.

·         Thomet, O. and Simon, H. Petasins in the treatment of allergic diseases: results of preclinical and clinical studies. Int Arch Allergy Immunol. 129(2):108-12, 2002.

·         Trauninger, A., et al.  Oral magnesium load test in patients with migraine.  Headache.  42(4):114-119, 2002.

·         Vogler B., et al. Feverfew as a preventive treatment for migraine: a systematic review. Cephalalgia. 18(10):704-8, 1998.  Review.

·         Wang, F., et al.  Oral magnesium oxide prophylaxis of frequent migrainous headache in children: a randomized, double-blind, placebo-controlled trial.  Headache.  43(6):601-610, 2003.

·         Welch, K. M., et al.  Mitochondria, magnesium and migraine.  J Neurol Sci.  134(1-2):9-14, 1995.

·         Woolhouse, M. Migraine and tension headache--a complementary and alternative medicine approach. Aust Fam Physician. 34(8):647-51, 2005.  Review.

What Makes Headrest™ Head Comfort Formula Unique?

People who are prone to head discomfort have different brain chemistry from those who rarely experience any head discomfort.  Sometimes the severity of head discomfort is not fully realized until it results in nausea, vomiting, sensitivity to light, noise or smells. For this reason, it is extremely important for those who often experience head discomfort to take regular steps to maintain head comfort. Two ways to help maintain head comfort are to maintain normal serotonin, which is a messenger that helps regulate the diameter of the blood vessels.  Fluctuations in serotonin cause the blood vessels in the brain to frequently expand and contract   causing discomfort. Another way to maintain head comfort is to help your body maintain proper circulation. 

Headrest™ Head Comfort Formula is specially formulated with Riboflavin (vitamin B2), magnesium, feverfew and butterbur, which work synergistically to help the body maintain healthy platelet activity thereby, reducing the frequency, severity and duration of head discomfort. Headrest helps maintain optimal blood flow to the brain, promotes normal sinus function, supports healthy blood vessel dilation, promotes healthy respiratory functions, which all help to maintain head comfort or work to support head comfort. In clinical trials in both Germany and the U.S., butterbur reduced the incidence of head cavity discomfort by up to 61 percent. Headrest supplies a healthy level of magnesium, which correlates with brain health (magnesium deficiency is common among head discomfort sufferers). In addition to promoting head comfort, Headrest supports a healthy immune system and promotes healthy cognitive function.*

Frequently Asked Questions About Headrest™ Head Comfort Formula:

Does Headrest™ contain caffeine?

No, Headrest does not contain caffeine.

Will taking Headrest make me drowsy?

Butterbur has the potential to cause drowsiness, but generally Headrest should be well tolerated.

What does PA Free mean and why is this important?

Pyrrolizidine alkaloid (PA) constituents are present in butterbur and have been shown to be hepatotoxic (liver toxic). The butterbur extract used in Headrest is PA-free and clear of all hepatotoxins.

How should I take Headrest?

HeadRest should be taken daily, in order to maintain head comfort. 

Who will benefit from Headrest?

Those who experience head discomfort.

What other Market America Products would compliment Headrest?

Isotonix^® Coenzyme Q10, Isotonix B-Complex, Isotonix Maximum ORAC, Isotonix MultiTech

Are there any warnings or contraindications for Headrest?

Yes. If you are currently taking diuretics, Cimetidine (anti-ulcer histamine blocker), antibiotics, warfarin (Coumadin), other anti-platelet/anti-coagulant medications, hydroxycholoroquine (antimalarial), corticosteroids, risedronate or other bisphosphonates, you should not take this product. Due to the magnesium content, you should not take this product if you have kidney failure. Feverfew may cause an allergic reaction in individuals sensitive to ragweed, chrysanthemums, marigolds or daisies. If you are taking any other prescription drugs or have an ongoing medical condition, you should consult your physician before using this product.  Women who are pregnant or nursing should not take this product.

How does this support normal sinus function?

Petasins, found in butterbur, have been shown to promote normal levels nasal inflammatory mediators associated with normal sinus function.

How do I take Headrest?

Take two capsules daily with food.